Warm, hearty, and packed with comfort, this Chicken and Stuffing Casserole is the ultimate weeknight dinner. Juicy shredded chicken mingles with creamy chicken soup, tender vegetables, and flavorful seasonings, all topped with a golden, buttery layer of stuffing. Each bite delivers the familiar tastes of a classic homemade meal, making it perfect for family dinners, potlucks, or cozy nights in.

The combination of creamy filling and crispy, golden stuffing topping is irresistible. Mixed vegetables add color and nutrition, while optional cheddar cheese brings a subtle richness to the dish. This casserole is both easy to make and versatile, allowing you to tailor it to your family’s tastes or pantry staples.

Why You’ll Love This Recipe

Comfort Food Classic: Delivers the flavors of a home-cooked meal in a single dish.
Easy to Make: Minimal prep and simple ingredients make it perfect for busy weeknights.
Family-Friendly: Loved by kids and adults alike.
Customizable: Add different cheeses, vegetables, or seasonings to suit your taste.
Make-Ahead Friendly: Assemble in advance for quick baking.
One-Pan Meal: Chicken, vegetables, and stuffing in one convenient dish.

Ingredient Breakdown

Shredded Chicken (3 cups): Provides protein and a hearty base; leftover rotisserie chicken works perfectly.
Chicken Broth (1 cup): Keeps the casserole moist and adds savory depth.
Cream of Chicken Soup (10.5 oz can): Creates a creamy, comforting texture throughout the casserole.
Stuffing Mix (6 oz package): Forms a crunchy, golden topping; traditional or seasoned varieties work well.
Mixed Vegetables (1 cup): Adds color, flavor, and nutrition; frozen or fresh vegetables are fine.
Garlic Powder (1 tsp) & Onion Powder (1 tsp): Enhance savory flavor without extra prep.
Black Pepper (½ tsp): Adds mild heat and seasoning balance.
Shredded Cheddar Cheese (½ cup, optional): Melts over the stuffing for extra richness and gooeyness.
Fresh Parsley (optional): Adds a fresh, vibrant finish.

Pro Tips

Use Rotisserie Chicken: Saves time and adds extra flavor.
Don’t Overcook Vegetables: If using fresh vegetables, lightly steam them beforehand to avoid soggy casserole.
Make It Ahead: Assemble the casserole up to a day in advance and refrigerate until ready to bake.
Crispier Topping: For extra crunch, broil the casserole for 1–2 minutes at the end of baking.
Cheese Options: Swap cheddar for mozzarella, Swiss, or a mix for different flavor profiles.

Ingredient Swaps or Variations

Vegetables: Use peas, carrots, green beans, broccoli, or a medley of your favorites.
Protein: Swap chicken for turkey or cooked.
Stuffing: Try cornbread stuffing or gluten-free varieties for dietary needs.
Creaminess: Substitute cream of mushroom or celery soup for cream of chicken soup.
Seasonings: Add thyme, sage, or rosemary for a more aromatic flavor.

Serving Suggestions

Serve alongside a fresh garden salad for a light contrast.
Pair with garlic bread or dinner rolls for a classic meal.
Add cranberry sauce or roasted vegetables for a holiday-style dinner.
Plate with mashed potatoes for extra comfort food vibes.

Make Ahead + Storage Tips

Storage: Refrigerate leftovers in an airtight container for 3–4 days.
Reheating: Reheat in the oven at 350°F (175°C) until warmed through. Cover with foil to prevent the topping from burning.
Freezing: Assemble but don’t bake, then freeze for up to 2 months. Thaw overnight in the fridge before baking.

Cultural or Historical Notes

Chicken and stuffing casseroles are a quintessential comfort food in American cuisine, often inspired by holiday meals. They are a practical way to repurpose leftover chicken and stuffing, making them a staple in family kitchens across the country. This casserole is an easy, weeknight-friendly version of the traditional dish, combining convenience with all the nostalgic flavors of a home-cooked meal.

Frequently Asked Questions (FAQ)

Can I use leftover turkey instead of chicken?
Yes, leftover turkey works beautifully and adds a holiday-inspired twist.

Can I make this casserole gluten-free?
Yes, use a gluten-free stuffing mix and ensure the cream soup is gluten-free.

Can I use fresh vegetables instead of frozen?
Absolutely, just lightly steam them first to avoid excess water in the casserole.

Can I prepare it ahead of time?
Yes, assemble it the day before and refrigerate. Bake just before serving for convenience.

Can I add extra cheese?
Yes, sprinkle extra cheese on top or mix it into the chicken layer for a richer flavor.

Emily