Easy High Protein Buffalo Chicken Cauliflower Casserole is a flavorful, low-carb comfort food packed with lean protein and bold buffalo flavor. Tender cauliflower florets and shredded chicken are coated in a creamy buffalo sauce and topped with melted mozzarella cheese.
This casserole is perfect for busy weeknights, meal prep, or anyone looking for a healthier alternative to traditional buffalo chicken dishes. The combination of Greek yogurt and cream cheese creates a rich, creamy texture while keeping the protein content high.
If you love buffalo chicken and want a satisfying, nutritious meal, this casserole is sure to become a regular favorite.
Why You’ll Love This Recipe
- High in protein: Loaded with chicken, Greek yogurt, and cheese.
- Low carb: Cauliflower replaces traditional starches.
- Easy to prepare: Simple ingredients and minimal prep.
- Perfect for meal prep: Reheats beautifully throughout the week.
About the Ingredients
Cauliflower
Cauliflower provides a hearty texture while keeping the casserole low in carbohydrates.
Chicken Breast
Shredded chicken breast adds lean protein and makes the dish filling and satisfying.
Buffalo Wing Sauce
Buffalo sauce delivers the signature spicy, tangy flavor that makes this casserole irresistible.
Greek Yogurt
Greek yogurt creates creaminess while boosting the protein content.
Mozzarella Cheese
Mozzarella melts beautifully and creates a bubbly, golden topping.
Tips & Tricks
Drain Cauliflower Well
Removing excess moisture helps prevent a watery casserole.
Use Rotisserie Chicken
Pre-cooked chicken saves time and adds convenience.
Adjust Spice Level
Add more or less buffalo sauce depending on your heat preference.
Pro Tips
- Roast cauliflower instead of steaming for deeper flavor.
- Add blue cheese crumbles for a classic buffalo chicken twist.
- Let the casserole rest for 5 minutes before serving.
Step-by-Step Instructions
Prepare the Cauliflower
Preheat oven to 400°F (200°C). Steam or boil cauliflower until tender-crisp, then drain thoroughly.
Make the Sauce
Whisk together buffalo sauce, Greek yogurt, cream cheese, garlic powder, and onion powder until smooth.
Combine Ingredients
Fold shredded chicken and cauliflower into the buffalo mixture until evenly coated.
Assemble the Casserole
Transfer the mixture to a baking dish and spread evenly.
Bake
Bake for 15 minutes, then top with mozzarella cheese and continue baking until melted and bubbly.
Garnish and Serve
Sprinkle with chopped green onions before serving.
Delicious Variations
Extra Cheesy Version
Add cheddar cheese along with mozzarella for extra richness.
Bacon Buffalo Casserole
Mix in cooked bacon for smoky flavor and crunch.
Vegetable Boost
Add broccoli or spinach for additional nutrients.
How to Store Easy High Protein Buffalo Chicken Cauliflower Casserole
Refrigerator
Store in an airtight container for up to 4 days.
Freezer
Freeze portions for up to 2 months.
Room Temperature
Do not leave out longer than 2 hours.
Reheating
Reheat in the oven or microwave until heated through.
Frequently Asked Questions
Can I use frozen cauliflower?
Yes, just thaw and drain it thoroughly before using.
Is this recipe keto-friendly?
It can fit into many low-carb and keto meal plans depending on the buffalo sauce used.
Can I use rotisserie chicken?
Absolutely, it’s a great time-saving option.
Can I make it ahead of time?
Yes, assemble the casserole and refrigerate until ready to bake.
What can I serve with it?
A side salad or roasted vegetables pair perfectly with this dish.